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KMID : 0388220140210010009
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Journal of the Korean Rheumatism Association
2014 Volume.21 No. 1 p.9 ~ p.19
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Dermatological Side Effects of Anti-tumor Necrosis Factor Alpha Therapy
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Moon Seong-Hun
Ko Joo-Yeon
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Abstract
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As anti-tumor necrosis factor alpha (anti-TNFα) agents are progressively being used in various medical conditions, dermatological adverse events have been encountered more frequently. To understand such dermatological con-ditions that have been documented while undergoing an-ti-TNF therapy, we reviewed relevant literature, including case reports and case series. Reported dermatological con-ditions included infusion and injection site reaction, cuta-neous infection, psoriasiform eruption, dermatitis, allergic rash, lupus-like lesion, vasculitis, lichenoid reaction, gran-ulomatous reaction, hair loss, cutaneous infection, and cu-taneous neoplasm. These events had varying strengths of causal association and severity therefore, drug dis-continuation may or may not be required.
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KEYWORD
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Anti-tumor necrosis factor, Dermatological, Side effects
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